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This modest reduction helps many people with hypertension, but the same mechanism can pose challenges for those who already struggle with inadequate blood pressure

A literature review found that megestrol acetate, a synthetic progesterone derivative, improved appetite and helped cancer patients gain weight (Ruiz Garcia 2013)

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PMID 8392011

It also modulates the rate of nutrient absorption, which can help stabilize blood sugar levels already being managed by your GLP-1 medication