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A recent randomized study comparing structured lifestyle modification (a cornerstone in the currently recommended treatment of NASH) to liraglutide 3 mg/day without lifestyle modifications showed similar reductions in ALT and liver stiffness with no difference in bodyweight variations

And so very much on a case-by-case basis

A history of pancreatitis Gallbladder problems Kidney disease Personal or family history of medullary thyroid carcinoma (MTC) (thyroid tumors) Multiple endocrine neoplasia syndrome type 2 (MEN2) Diabetic retinopathy High triglyceride levels Any digestive disorders Additionally, pregnant women, women who are trying to conceive, or women who are breastfeeding may not be prescribed semaglutide

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This makes it one of the faster-acting options when arousal pathways are involved