Growth hormone replacement therapy medications are approved by the Food and Drug Administration to treat both young children with short stature, in addition to being considered incredibly safe to use in adults that have a deficiency of Human Growth Hormone
Conversely, although off-label use of GLP-1 RA for overweight and obesity cannot be excluded, such use was likely limited in the present study given existing prescription guidelines and regulatory vigilance
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Larger deficits mean larger nutrient gaps, so the higher-efficacy drugs raise the stakes on protein and testing, not the shopping list