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This pressure gradient is highly regulated by a dual feedback system, which can be manipulated pharmacologically to upregulate water transport through the lens and subsequently increase the delivery of antioxidants to the core region of the lens to prevent age-related nuclear cataracts

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And some of these symptoms are more common in adults than in children

In animal models, GIP agonists were shown to have beneficial effects on tissue-level bone material properties

As such, tirzepatide is anticipated to receive marketing approval by mid-to-late 2022

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