Interestingly, RNA viruses, such as SARS-CoV-2, HIV and DENV, also activate the cGAS-STING axis, despite cGAS being a DNA PRR (36, 46, 147)
It modulates key factors in the tissue repair process, making it useful in post-surgical recovery and general wound care.
Therefore, it is also named GI-GPX or GPX-GI
however, their use is hindered by ethical considerations
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This comprehensive perspective not only deepens our understanding of ACL injuries but also fosters the development of evidence-based, individualized interventions that address the unique needs of each individual.