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Clin Gastroenterol Hepatol 2024;22:705707.ArticlePubMed 40

There is mounting evidence for the role of oxidative stress in the pathophysiology of depression

What it is not is a proven cure for illness or a way to reverse aging, and the evidence for generic wellness drips is weak

Experimental verification showed that the inhibition of the mitochondrial ROS-mediated pathway enhances insulin production from pancreatic cells [88], subsequently causing ferroptosis due to the accumulation of lipid peroxides [89]

And its anabolic-related genes include fibroblast growth factor-21 (FGF21), SREBP-1c, fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC-a), liver X receptor (LXR), suppressor of cytokine signaling-3 (SOCS-3), etc

Following medium change, cells were treated as indicated