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However, adequate adjustment of insulin doses and close monitoring after GLP-1RA initiation may decrease this risk

It indicates that there will be a rise in cases of type 2 diabetes in adults

Biermanns patients can eventually take their medication less frequently, why cant they start doing that off the bat

The liver contains GLP-1 receptors, and activation appears to directly reduce hepatic lipogenesis (fat production in the liver), increase fatty acid oxidation, and reduce inflammatory signaling in hepatocytes

And anyone with a personal or family history of medullary thyroid carcinoma should not use tirzepatide regardless of autoimmune status

doi: 10.1016/j.neuropharm.2018.03.030 2 AlvaradoM