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However, there are situations in which GLP-1 agonists should be discontinued in perioperative care such in cases of acute kidney injury requiring renal replacement therapy and in cases of postoperative ileus (Hurst, et al., 2021)
The former induces muscle atrophy by hydrolyzing myosin within myofibrils, while the latter may inhibit protein synthesis by downregulating the expression of eIF3f and MyoD, leading to muscle atrophy (71,72)
Prospective randomized evaluation of idiopathic hyperoxaluria treatments
H., Riddell, R
Notably, the effects of a GLP-1 receptor agonist during anticipatory and consummatory phases of food reward revealed opposing changes in brain responses, reducing anticipatory while enhancing consummatory reward responses (van Bloemendaal et al., 2015a)
(2022) LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist Cell Metab 34(9):1234-1247
