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Phase 2 data reported nausea (~42%), vomiting (~20%), and diarrhoea (~18%) in the highest dose cohort, consistent with the GLP-1 class

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This uncertainty does not mean the compound is ineffective or dangerous

Gastrointestinal adverse events - predominantly nausea, vomiting, diarrhea, and constipation - are the most common class effects, occurring in 20%-60% of patients depending on the agent and dose, and are typically of mild-to-moderate severity, dose-dependent, and most prominent during titration