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A pooled analysis of semaglutide trials reported thyroid adverse events in less than 1% of participants

MHRA GLP-1 Medicines for Weight Loss and Diabetes: What You Need to Know (GOV.UK, updated 2026) 3

Heres what each one does to potentially help with weight loss, what the research shows, and whether it makes a difference

for reference, the Wegovy (semaglutide 2.4 mg) UK SmPC advises stopping treatment at least two months before a planned pregnancy

The key difference is the length of that window, not the quality within it

Theres currently no known pharmacological interaction between coffee and semaglutide, so drinking coffee while on treatment is considered safe