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Milicic A, Kaur R, Reyes-Sandoval A, Tang CK, Honeycutt J, Perrie Y, Hill AV

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Patients with gastroparesis or severe gastrointestinal disorders may need alternative approaches due to tirzepatide's effects on gastric emptying

These medications slow gastric emptying and suppress appetite, which may reduce oral intake while increasing losses of sodium, potassium, magnesium, and other essential minerals