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Rare but serious side effects ( 10%), including nausea, constipation or diarrhea, loss of appetite/feeling of fullness, and acid reflux
This "clean" pharmacological profile makes Ipamorelin the preferred reagent for researchers aiming to isolate the somatotropic (growth hormone) pathway without introducing the confounding variables of stress hormone elevation or appetite stimulation
Neurobiol Dis (2019) 124:189201
Andrew Huberman: Great, that's very useful information, I'm sure, to a number of people out there
But what exactly is it, and why is it so important
Reported or theoretically plausible side effects of CJC 1295 and ipamorelin include: Water retention and peripheral oedema Flushing, headache, and dizziness, particularly after injection Tingling or numbness in the extremities Elevated IGF-1 levels, which over time may theoretically increase the risk of certain cancers, though a direct causal link has not been established in clinical studies [13] [14] Impaired glucose tolerance or insulin resistance GH excess and GH secretagogues are more commonly associated with raised blood glucose rather than hypoglycaemia
