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This could explain the direct damage in some of these patients and the alteration of the HPA axis ( Regarding direct damage due to the immune system, it has been suggested that there is a high molecular similarity between SARS-CoV-2 peptides and human adrenocorticotropic hormone, as in the case of SARS-CoV viral peptides that are structurally similar to adrenocorticotropic hormone (ACTH) (36, 39, 40)

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