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(As a side note, I was intrigued that the control group had lower medical costs than the GLP-1 users, and materially lower medical + Rx costs, at the end of the second year regardless of the higher trend.) That total cost picture aligns more closely with my expectations and experience, but differs a lot from the headline message
Research suggests that dose escalation schedules are associated with better tolerability compared to starting at a higher dose right away
Replenish the Fuel (NAD Precursors) Supplementation with NMN (Nicotinamide Mononucleotide) or Nicotinamide Riboside can directly replenish cellular NAD levels, giving the mitochondria enough fuel to produce energy and allowing the repair crew to do its job without stealing everything
In doing so, it stimulates insulin release, inhibits the production of glucagon (a hormone that raises blood sugar levels), and slows gastric emptying (the speed at which food moves through your digestive tract)
Kamble M, Gupta R, Rehan HS, Gupta LK
10.1007/s00125-012-2534-0 74
