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The article says clinical trials show dulaglutide reduces HbA1c by 1.5 to 2 percent and improves cardiovascular outcomes in high-risk patients, and that provider assessment of kidney function and thyroid history informs safe use

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They may also improve insulin resistance for people with PCOS

BAs could signal through the cell surface GPBAR1/TGR5 in brown fat and skeletal muscle cells to increase energy expenditure and prevent diet-induced obesity

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