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At the tissue level, GLP-1 agonists diminish ectopic fat accumulation in the liver and muscle, enhancing insulin sensitivity

Ex-4 modulates apoptotic pathways in the hippocampus through the regulation of the expression levels of Bcl2, Bax, and caspase-3 [71], and it improves mitochondrial function and integrity in AD mice through the PI3K/Akt signaling pathway [72]

Various pre-clinical and clinical studies have revealed the hepatoprotective effect of semaglutide in NASH and neuroprotective effect in Parkinsons and Alzheimers disease

Of note, he recently started Ozempic for weight loss, he explained to Medical News Today

Suspected side effects may also be reported directly via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk) or the Yellow Card app

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