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452 Endothelial cells exhibit enhanced NO production and concurrent suppression of endothelin formation, resulting in vascular smooth muscle relaxation and vasodilation mediated by the endothelium (e.g., GLP-1, exenatide, and liraglutide)

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Regulatory update (April 2026): This peptide was removed from the FDA's Category 2 'Do Not Compound' list effective April 22, 2026

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