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The synthetic triterpenoid compound bardoxolone methyl (bardoxolone) has also been studied for potential therapeutic applications in various diseases, such as in clinical trials for the treatment of chronic kidney disease, type 2 diabetes, and Alport syndrome [460,461,462,463]
Topical niacinamide stabilizes the epidermal barrier function with increased protein and ceramide synthesis and keratinocyte differentiation, improving skin microrelief and attenuating fine wrinkles
This reduction results in lighter and even skin tone
Trends in Food Science & Technology, 141 , 104201
Therefore, when curcumin and lauric acid liposomal gels are combined for therapy, there is a notable decrease in IL-1 and TNF- levels by around 1.9 and 2.5 times, indicating its effectiveness in treating acne [332]
Xueqiang Z, Yu Z, Wendong L, Shuying F, Jie H
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