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These red flags apply universally

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To keep patients safe and outcomes strong, consider the following clinical best practices: Start low, go slow on dosing Monitor for GI symptoms, especially early on Revisit mental health and vision concerns routinely Avoid use in patients with thyroid cancer history Stay alert for signs of pancreatitis or gallbladder issues Smart oversight matters

The significance of NADPH levels to cellular survival has been demonstrated by overexpression of several cytoplasmic enzymes that synthesize NADPH leading to lifespan extension in model organisms such as Drosophila melanogaster

Alexandra Sowa, MD, is an obesity medicine specialist and author of the upcoming book The Ozempic Revolution