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Perhaps their most important effect is that they slow down the emptying of the stomach

But research currently lags behind the trend, with the evidence around tirzepatides effectiveness based on therapeutic doses of at least 2mg

"Anti-Diabetic Actions of GLP-1-Based Therapies beyond Glucose Control." Int J Mol Sci

Patients with pre-existing gastrointestinal conditions may experience different responses to semaglutide, though specific susceptibility patterns have not been well-established in clinical studies