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Hepatocyte cholesterol content modulates glucagon receptor signalling

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Ferroptosis is initiated by iron-dependent lipid peroxidation, marked by the accumulation of ROS, malondialdehyde (MDA) buildup and iron overload

The two drugs are metformin, one of the most widely used diabetes medications, and the GLP-1 class of medications that include Ozempic, Mounjaro and Saxenda

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