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342 However, the damaged mitophagy leads to ROS accumulation, inflammasome activation, and lipid accumulation, which results in cell damage
NutrMetab (Lond)
Science 365 , eaav9518 (2019)
Patients who remained on treatment throughout the study achieved even greater average weight loss, demonstrating the importance of adherence and gradual dose escalation
( c ) Example cells of transient cAMP responses
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