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Growth Factors Upregulated by Uric Acid Affect Guanine Deaminase-Induced Melanogenesis

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GSH helps maintain redox homeostasis by reducing biomolecules such as sulfhydryl groups

It also upregulates cardiac-enriched microRNAs, creating a vicious cycle involving abnormal myosin heavy chain expression, autophagy inhibition, and impaired mitochondrial fatty acid oxidation (Park et al., 2023)

In experimental models, researchers may explore processes such as pulsatile hormone release dynamics, receptor-mediated signaling, and downstream metabolic pathway modulation