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Bariatric Surgery and Type 2 Diabetes Mellitus: Assessing Factors Leading to Remission

Carnitine O -acetyltransferase Carnitine O -acetyltransferase (CrAT), located primarily in the mitochondrial matrix, catalyzes the addition or the removal of carnitine from medium- and short-chain acyl-CoA 60,61 , facilitating the efflux of mitochondrial acetyl-CoA to the cytosol and buffering the intracellular pools of acetyl-CoA and carnitine

Presenilins are required for -secretase cleavage of -APP and transmembrane cleavage of Notch-1