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Ischemia-reperfusion injury The heart muscle may become oxygen-deprived (ischemic) as the result of myocardial infarction or during cardiac surgery
insulin is broken down by the stomach acid Concentration the higher the concentration, the more drug that is absorbed (usually!) Ionisation ionised particles cannot diffuse across membranes this plays a part in the mechanism of action for local anaesthetics Solubility drugs that are more polar (see below) are less readily absorbed through the lipid bilayer of the cell membrane Physical state of the drug e.g
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Administering Wegovy in the thigh requires proper technique to ensure the medication reaches the subcutaneous tissue and to minimise discomfort or complications
Nemoto, S., Fergusson, M
Ozempic Sulphur Burps and Diarrhoea: Causes, Duration and Management Ozempic (semaglutide), a GLP-1 receptor agonist for type 2 diabetes, commonly causes gastrointestinal side effects including diarrhoea and sulphur burps
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