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Plasma lipoic acid concentrations generally peak within one hour or less and decline rapidly (6, 7, 11, 12)

Although various supportive strategies to reduce hepatotoxicity, such as drug dose reduction, hyperhydration, and antioxidant supplementation (e.g., silymarin, N-acetylcysteine), are commonly used to manage chemotherapy-induced hepatotoxicity, none constitutes a definitive or standard treatment

If you havent started to notice any difference to your symptoms after 12 weeks then you should contact your doctor, although you should receive regular monitoring from your doctor via appointments and/or blood tests

They are generally well tolerated