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Let's break down what that means for medical practice and your business

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

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So I very much try to avoid, want to avoid, and usually can periods of estrogen deprivation from my patients

Supplementing with a bioavailable form of glutathione directly ensures your body has the "finished product" ready for use

They bind selectively and with high affinity to glutamate-gated chloride ion channels present in invertebrate nerve and muscle cells