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I was TGI on meso
& Begaud, B
542-559, www.sciencedirect.com/science/article/pii/S1525861013003265
The FDA also looked at postmarket safety data from Japan, where the drug was launched in 2020
Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine
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