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Retatrutide was associated with a greater increase in resting heart rate than tirzepatide in clinical trials
From a mechanistic point of view, glucose uptake into brown adipose tissue seems to play an important role
Sano M, Takei M, Shiraishi Y, Suzuki Y
10.1016/j.bbr.2023.114300 105 MousavinejadE.GhaffariM
Butyrate acts through HDAC inhibition to enhance Aryl hydrocarbon receptor activation by gut microbiota-derived ligands
Clinicians use that context to decide whether a shifted value needs follow-up, represents an expected therapeutic response, or signals an adverse event
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