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As of March 2025, 11 states cover GLP-1s for weight loss under their state employee health plan, nine states provide coverage under their state Medicaid program, and five states provide coverage under both programs

The gender distribution revealed that 57.5% of reports involved female patients, while male patients accounted for 40.5%, with the remaining 2.0% lacking gender specification

Guidelines suggest the additional use of DPP-4 inhibitors after metformin failure in patients that do not require antidiabetic therapy with proven cardiovascular benefit

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Changes in renal function may also occur in patients experiencing significant weight loss, as glomerular hyperfiltration associated with obesity improves