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Sin embargo, estos resultados tienen limitaciones importantes que conviene explicitar: La extrapolacin de roedores a humanos es notoriamente poco fiable en toxicologa

In preclinical studies, mice fed a high-fat diet and treated with 5 amino 1mq for just 11 days experienced remarkable metabolic improvements

These drugs also exhibit additional benefits, such as cardio- and neuroprotection, anti-inflammatory properties, and modulation of reward and food intake behaviors

Therefore, in analyses regarding fatigue and sleep impairment, we chose to use levels of androsterone sulfate, an indicator for the effectiveness of ADT (Figures 1E, 3)