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The meniscus contains regions with varying blood supply, meaning some tears have a greater capacity for healing than others
Given 40-60% nasal bioavailability compared to 80-95% for injection, equivalent nasal doses would be approximately 400-1000mcg to achieve similar systemic levels
Activated Akt then phosphorylates eNOS at Ser1177, directly increasing nitric oxide production
One approach, he said, involves packaging peptides inside nanoparticles, microscopic carriers designed to protect the drugs and help deliver them more effectively to their intended targets
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