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Observed differences in weight loss were significant for those who had a diagnosis of obesity (either or without comorbid T2DM), but not for those with T2DM only

Glutathione also is a naturally occurring antioxidant that is formed within your cells

Once-weekly semaglutide in adults with overweight or obesity (STEP 5)

Mouth sores, if they occur, may be multifactorial and warrant clinical assessment to exclude other causes such as viral infections, nutritional deficiencies (particularly vitamin B12, which can also be associated with metformin use in type 2 diabetes, folate, or iron), or autoimmune conditions

Diarrhoea may result from altered gut motility and changes in intestinal fluid secretion, whilst constipation can occur due to overall slowing of gastrointestinal transit

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