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Posteriormente, el mdico podr ajustar la dosis segn la respuesta clnica y los objetivos teraputicos

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Published Phase 2 data shows: Dose Group Discontinuation Due to AE Placebo 0% 1 mg 2.9% 4 mg (escalated) 5.7% 8 mg (escalated) 5.0% 12 mg (escalated) 8.3% For context, discontinuation rates in semaglutide 2.4 mg trials (STEP program) were approximately 7%, and tirzepatide 15 mg trials (SURMOUNT) reported approximately 6-7%

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Many patients notice the slowdown in the first 24 weeks

Zheng YJ, Soegiharto C, Au HCT, Valentino K, Le GH, Wong S, et al