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Not only are newer orals like orforglipron less expensive to produce because they dont include devices, like prefilled syringes or injectors, but orforglipron isn't a protein-based molecule
Ozempic is currently only FDA-approved for the treatment of type 2 diabetes mellitus to help improve the control of blood sugar levels and to reduce the risk of cardiovascular problems in patients with Type 2 diabetes and cardiovascular disease
Transdermal delivery of GLP-1 medications faces significant challenges due to the large molecular size of GLP-1 analogs and the skin's natural barrier function
Image transferred from 35 mm slide: Jay Vannini 2022
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Guan X, Dwivedi C, Kim SY, Fine T, Ratzsch A, Seefeldt T, et al
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