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GSH represents a significant part of the redox status of thiol mammalian systems [2, 3]
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This increased tolerance results from the brain adapting to opioid exposure, reducing its responsiveness to the drug
Nonspecific sites on the membranes were blocked with tris-buffered saline (TBS) that contained 5% nonfat milk and 0.1% Tween 20 (TBST, Beyotime, China) for 2 h
Investigations focus on its effects in weight loss, glucose regulation, and energy balance, showing potential therapeutic benefits for obesity, type 2 diabetes, and other metabolic disorders in experimental models
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