Fact Sheet for health professionals, National Institutes of Health (NIH)
Further analyses revealed that changes in blood GSH were highly correlated with those in erythrocytes, and changes in lymphocyte GSH were significantly correlated with those in both blood and erythrocytes
10.1146/annurev.nutr.18.1.39 Annu
Oral GLP-1s for obesity saw a recent setback when in April (April 2025), Pfizer announced that it was discontinuing development of danuglipron, an oral GLP-1 receptor agonist, which was being investigated for chronic weight management, due to potential liver toxicity
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But because those studies followed different groups of people over different periods of time, researchers eventually compared the medications head-to-head in a roughly 16-month clinical trial involving more than 750 adults with obesity