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Consistent with the incretin-mediated delivery of the PPAR// agonist, the metabolic effects of GLP-1GIPLani were blunted in DIO mice with pharmacological or genetic inhibition of GLP-1R, GIPR or PPAR, and vanished in double-incretin receptor knockout (DIR-KO) mice

Rooted in common law, the Learned Intermediary Doctrine provides that a pharmaceutical company does not have a duty to warn the consumer directly and shifts the duty to warn onto the patients prescribing physician

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Lauren Young: Thanks so much for having me