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The clinical program of the cagrilintide + semaglutide combination (CagriSema) is being developed in two main phase 3 studies REDEFINE 1 (obesity) and REDEFINE 2 (type 2 diabetes)

Wegovy is FDA-approved specifically for chronic weight management in adults with obesity or overweight with a related health condition

Both support the same biological endpoint -- higher intracellular glutathione -- at different points in the pathway (precursor supply vs direct delivery)

Retatrutide is currently progressing through Phase 3 clinical trials, representing the final stage before potential regulatory approval

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