Recent epidemiological studies have shown that a long-term Western diet affects the microbiota-gut-brain axis and promotes the development of neurodegeneration, leading to the development of PD (Figure 3D) (127, 128)
These interrelated processes contribute to complications of diabetes including endothelial dysfunction, atherosclerosis, diabetic nephropathy, and other chronic diseases (Giri 2018)
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1987, 22: S132-135
In supervised studies with the GHRH analog tesamorelin, IGF-1 stayed within the age-normal range, and insulin-stimulated glucose uptake was preserved (Stanley et al., 2011)