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Individuals with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use these medications

Pastor-Maldonado CJ, Surez-Rivero JM, Povea-Cabello S, lvarez-Crdoba M, Villaln-Garca I, Munuera-Cabeza M, Surez-Carrillo A, Talavern-Rey M, Snchez-Alczar JA

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For instance, Hu et al

Long-Term Mortality in Elderly Khavinson et al., observational follow-up data Khavinson and colleagues conducted long-term observational follow-up of elderly patients receiving courses of pineal peptide preparations (including epithalamin and related compounds) and reported a 1.61.8-fold reduction in all-cause mortality over 23-year follow-up periods compared with untreated control groups

However, other studies have raised concerns about the effects of chronic carnitine exposure on the cardiovascular system