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The researchers searched social media platforms for posts that mentioned tirzepatide (and similar drugs used for weight loss) and related mental health issues

Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H

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Your doctor will review your recent HbA1c levels (a measure of average blood glucose over the previous 2-3 months), your current diabetes medications and doses, any history of hypoglycaemic episodes, and your ability to recognise and manage low blood sugar

While still investigational and awaiting FDA approval, retatrutide shows that targeting multiple pathways at once can get close to surgical weight loss numbers, without surgery