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This is the axis that links the remaining mechanisms: protection of cells against damage while simultaneously supporting vessel formation and the migration of repair cells

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It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported

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24 It must be mentioned that the study had a low patient number of n = 14 and was performed in children with a mean age of 11.8 years when trauma occurred