The short half-life means drug accumulation from a double dose can cause severe GI side effects
Vida Hormone Therapy Miami (Kendall) Known For: A former University of Miami professor with Tulane training and an anti-aging fellowship, prescribing bioidentical hormones and peptides since 2005
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Tirzepatide (commonly prescribed as Mounjaro) belongs to the class of GLP-1/GIP receptor agonists that have revolutionized weight loss treatment
Gout There are some limited studies in patients with gout, some reporting a possible flare of gout when therapy with GLP1 is started, mostly due to rapid weight loss and dehydration that may precipitate gout attacks
The authors proposed peripheral mechanisms such as reduced genital blood flow and central modulation of dopamine and noradrenaline in brain regions regulating reward and arousal