Body-weight changes, the frequency of severe food-preoccupation episodes, and temporal correlations between biomarker emergence and symptom recurrence were also evaluated to explore associations, rather than causal effects, between tirzepatide exposure and NAc oscillatory activity
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This is a major policy shift Medicare has historically excluded weight-loss drugs under the Part D anti-obesity exclusion
The researchers concluded that semaglutide was well tolerated over 52 weeks when used in conjunction with dietary and exercise counseling and demonstrated clinically meaningful weight loss as compared to placebo at all doses
Patterson JT, Ottaway N, Gelfanov VM, Smiley DL, Perez-Tilve D, Pfluger PT et al