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77 MikusD.SikiricP.SeiwerthS.PetricevicA.AralicaG.DruzijancicN.et al (2001)

Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimers disease dementia: a phase 1 clinical trial

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doi: 10.1038/ng.257 46

The mechanism involves upregulation of tissue inhibitors of metalloproteinases (TIMPs) and simultaneous downregulation of matrix metalloproteinases (MMPs), shifting the extracellular matrix balance toward net deposition rather than degradation

Studies show comparable results to full-time bracing for appropriate candidates