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Wegovy has faced persistent supply shortages since its launch

Others require emergency intervention if vomiting is uncontrollable, blood sugar drops below 54 mg/dL, or signs of dehydration (extreme thirst, dry mouth, decreased urination) persist

Elevated blood pressure and increased heart rate can also occur, especially in the first three months

Guo J, Meng F, Hu R, Chen L, Chang J, Zhao K, et al

Simply stated: nalmefene is a mixed mu antagonist, KOR partial agonist FDA-approved for clinical use to acutely reverse respiratory depression during opioid overdose

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