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Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause

Cyclophosphamide can cause Hemorrhagic cystitis followed by the events of oxidative stress supported by a low activity of Nrf2

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To ensure genetic fidelity and exclude contamination, the identities of the PDX models were rigorously monitored through the establishment a backup library, control of passaging number, and performing short tandem repeat (STR) profiling specificity

It's based on Nobel Prize-winning research