In the application note Comparison of thioredoxin activity in cortical neuron and glial cells using a BMG LABTECH microplate reader a thioredoxin system that contains sulfhydryl groups protected cells against H 2 O 2 -induced cell death and its inhibition promoted oxidative stress, while thioredoxin-overexpressing mice displayed less oxidative brain damage following ischemia and lived longer
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Bull Natl Res Cent 48 , 100 (2024)
M., Nygard, O
Yes, foods rich in sulfur-containing amino acids, such as garlic, onions, and cruciferous vegetables, can support glutathione production
Tebay LE, Robertson H, Durant ST, Vitale SR, Penning TM, Dinkova-Kostova AT, Hayes JD