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A 2019 FDA Drug Safety Communication specifically warned that gabapentinoids can cause serious breathing problems when combined with CNS depressants or in patients with underlying respiratory compromise [5]

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Subsequent research expanded into broader investigations involving vascular and inflammatory mechanisms

Cell viability was assessed 3 days after treatment with FOXO4-DRI at 0, 12.5, 25, 50, and 100 M, respectively, using the Cell Counting Kit-8 (CCK-8) Assay (Dojindo, Rockville, MD, United States)

As this technology becomes more widespread, its integration into standard medical protocols appears inevitable

Deficiency leads to nerve damage (neuropathy), which presents as numbness, tingling, or weakness